How to Lower SGPT and SGOT Levels in Liver

Explore comprehensive strategies to reduce SGPT and SGOT levels in your liver, including dietary adjustments, lifestyle changes, and medical advice.
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3 min
23-September-2024

The liver plays a crucial role in maintaining overall health by managing digestion, metabolism, detoxification, nutrient storage, and protein synthesis. Despite its importance, it's often one of the most overlooked organs in the body. While many associate liver damage primarily with alcohol consumption, several other factors can impact its health.


Two key enzymes—SGPT (Serum Glutamate Pyruvate Transaminase), now commonly called ALT (Alanine Aminotransferase), and SGOT (Serum Glutamic-Oxaloacetic Transaminase), also known as AST (Aspartate Aminotransferase)—serve as important markers of liver function. When the liver is damaged, these enzymes leak into the bloodstream, leading to elevated SGOT and SGPT levels, signaling potential liver distress.

What is the meaning of SGPT in liver?

SGPT, also known as ALT (Alanine Transaminase), is an enzyme found in liver cells. It plays a vital role in converting proteins into energy for liver function. When liver cells are damaged due to conditions like hepatitis, fatty liver disease, or alcohol abuse, SGPT levels rise in the bloodstream. High SGPT levels are often a sign of liver inflammation or injury. Many people wonder how to lower SGOT and SGPT levels, as doing so is crucial to preventing long-term liver damage.

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What is the meaning of SGOT in liver?

SGOT, also known as AST (Aspartate Aminotransferase), is another enzyme primarily found in the liver but also in muscles, heart, kidneys, and brain. Like SGPT, SGOT levels increase when the liver or other tissues are damaged. Elevated SGOT levels can indicate liver diseases, but they may also suggest heart or muscle injury. People who want to know how to lower SGOT and SGPT levels should focus on maintaining a healthy lifestyle and addressing any underlying liver conditions promptly.

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What is the SGPT and SGOT normal range?

The normal levels of Serum Glutamic-Oxaloacetic Transaminase (SGOT) and Serum Glutamic-Pyruvic Transaminase (SGPT) may vary slightly depending on laboratory methods and testing standards. However, the following reference ranges are generally accepted:

Test

Normal Range (Units/Litre)

SGOT (AST)

5 to 40 U/L

SGPT (ALT)

7 to 56 U/L

These values help assess liver health and identify potential issues when elevated.

What are the causes of high SGPT and SGOT levels?

Several factors can lead to elevated SGPT and SGOT levels in the blood. Some of the most common causes include:

  • Liver diseases: Conditions like hepatitis, fatty liver disease (AFLD/NAFLD), and cirrhosis are major contributors to increased liver enzyme levels.

  • Excessive alcohol consumption: Chronic alcohol use is a leading cause of liver damage, often reflected in elevated SGPT and SGOT.

  • Medications: Certain drugs such as statins, acetaminophen, and antibiotics can be harmful to the liver and raise enzyme levels.

  • Gallbladder inflammation (Cholecystitis): This can disrupt bile flow and liver function, resulting in higher enzyme counts.

  • Muscle injury: Since SGOT and SGPT are also found in muscles, any muscle damage can lead to temporary elevation.

  • Obesity and Diabetes: Both are risk factors for non-alcoholic fatty liver disease, contributing to increased enzyme levels.

  • Other health conditions: Issues like heart attacks or congestive heart failure can indirectly damage liver cells and elevate these enzymes.

 

What are the symptoms of high SGPT & SGOT in the liver?

When SGPT and SGOT levels are elevated, it often signifies liver stress or damage. Early detection of these symptoms can lead to timely interventions. Here are some common signs of high SGPT and SGOT:

  • Fatigue

  • Weakness

  • Nausea and vomiting

  • Shortness of breath

  • Swelling in both legs

  • Jaundice

  • Excessive bleeding

  • Abdominal Discomfort

  • Weight loss

  • Change in stool colour to pale yellow

  • Yellowing of skin and whites of the eyes

  • Pain and swelling in the abdomen, where the liver is present

  • Dark colour in urine

  • Swelling in the ankles

  • Frequent skin itching

  • Loss of appetite

Recognising these symptoms early can help in diagnosing elevated SGPT and SGOT levels and determining how to lower them effectively.

How to reduce SGPT and SGOT quickly?

Lowering SGPT and SGOT levels quickly is essential for preventing liver damage. Some lifestyle changes and practices can help normalise these enzymes:

1. Healthy diet:

Include more fruits, vegetables, whole grains, and lean proteins to support liver function. Foods rich in antioxidants, like berries and green leafy vegetables, are particularly beneficial for liver health.

2. Hydration:

Drink plenty of water to help the liver flush out toxins and regulate enzyme levels.

3. Exercise regularly:

Moderate physical activity helps in maintaining a healthy weight and reducing liver fat, which can lower SGPT and SGOT levels.

4. Avoid alcohol:

Alcohol is a significant contributor to liver damage. Limiting or completely avoiding it can help in reducing elevated liver enzymes.

5. Limit processed foods:

Avoid processed foods, excessive sugar, and unhealthy fats, which can stress the liver and elevate enzyme levels.

6. Liver-friendly supplements:

Herbs like milk thistle and turmeric have been shown to support liver health.

These practices will not only lower SGPT and SGOT levels but also promote overall liver health.

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Medical treatments and supplements for lowering SGPT and SGOT

In some cases, medical treatments and supplements may be necessary to reduce SGPT and SGOT levels. It is essential to consult a healthcare provider before starting any treatment. Some common options include:

1. Prescription medications:

In cases of liver inflammation or hepatitis, doctors may prescribe antiviral or anti-inflammatory medications to reduce liver stress and lower enzyme levels.

2. Milk thistle supplements:

Known for its liver-protective properties, milk thistle can help in reducing liver enzyme levels.

3. Turmeric supplements:

The active compound in turmeric, curcumin, has anti-inflammatory and antioxidant effects that can lower SGPT and SGOT levels.

4. Vitamin E and C:

These vitamins have antioxidant properties that protect the liver from oxidative stress and help in reducing enzyme levels.

5. Statins for fatty liver:

If the cause of elevated enzymes is fatty liver disease, statins can be prescribed to reduce cholesterol levels and improve liver function.

Proper medical guidance is crucial in choosing the right treatment to lower SGPT and SGOT levels effectively.

Monitoring and managing liver health effectively

Effective liver health management requires regular monitoring of SGPT and SGOT levels. Here are some steps you can take to keep your liver in check:

1. Regular blood tests:

Periodically check your liver enzyme levels through blood tests to monitor liver function.

2. Liver Function Tests (LFTs):

Your doctor may recommend LFTs to assess overall liver health and ensure that SGPT and SGOT levels are within normal ranges.

3. Healthy lifestyle:

Continue with healthy eating habits, regular exercise, and avoiding alcohol and tobacco to maintain liver health.

4. Consult with healthcare providers:

Regular health check-ups with a healthcare provider can help in early detection of liver issues and timely interventions.

5. Health insurance coverage:

Given the rising costs of medical treatments and liver-related care, having a comprehensive health insurance plan can help cover expenses related to liver health, including medications, diagnostic tests, and hospitalisations. Many insurance providers offer plans tailored to liver care, which can be highly beneficial in managing long-term liver health.

Elevated SGPT and SGOT levels are often indicators of liver damage or inflammation, and they require immediate attention to prevent further complications. By adopting a healthy lifestyle, incorporating liver-supportive supplements, and seeking medical treatments, individuals can lower SGPT and SGOT levels effectively. Additionally, regular monitoring and health insurance play a pivotal role in managing liver health. Health insurance can cover the costs of diagnostic tests, treatments, and hospital visits, making it an essential component in maintaining long-term liver wellness. Taking proactive steps now can help safeguard your liver and overall health for the future.


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Frequently asked questions

What are normal SGPT and SGOT levels?
Normal SGPT levels typically range between 7-35 units per litre for women and 10-40 units per litre for men. Normal SGOT levels range from 13-35 units per litre for women and 15-40 units per litre for men.

How long does it take to lower SGPT and SGOT levels with lifestyle changes?
With consistent lifestyle changes, such as improved diet, regular exercise, and avoiding alcohol, SGPT and SGOT levels may start lowering within a few weeks to months, depending on the individual’s liver condition.

Can certain medications affect SGPT and SGOT levels?
Yes, certain medications, including statins, antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs), can elevate SGPT and SGOT levels as they may cause liver stress or inflammation when metabolised.

What are the signs of high SGPT and SGOT levels that I should be aware of?
Signs of high SGPT and SGOT levels include fatigue, jaundice, abdominal pain, dark urine, nausea, loss of appetite, and itchy skin. These symptoms suggest liver dysfunction and require prompt medical attention.

How can I reduce my SGOT and SGPT levels?

You can reduce elevated SGOT and SGPT levels by improving your liver health through the following:

  • Follow a liver-friendly diet (fruits, vegetables, whole grains, lean proteins)

  • Avoid alcohol and tobacco

  • Exercise regularly to maintain a healthy weight

  • Stay hydrated to support detoxification

  • Limit processed and fried foods

  • Manage diabetes and cholesterol if applicable

  • Avoid unnecessary medications that strain the liver

Which foods reduce SGOT and SGPT?

Some of the best foods to help lower SGOT and SGPT levels include:

  • Leafy greens like spinach and kale (rich in antioxidants)

  • Beetroot and carrots (promote liver detox)

  • Berries (blueberries, strawberries – fight inflammation)

  • Garlic and turmeric (natural anti-inflammatory agents)

  • Apples, grapes, and citrus fruits

  • Green tea (contains catechins that support liver health)

How do you normalize SGOT and SGPT levels?

To normalize your SGOT and SGPT levels:

  • Eat a balanced, anti-inflammatory diet

  • Avoid alcohol and liver-damaging substances

  • Include regular physical activity

  • Monitor your medications and consult a doctor for alternatives if needed

  • Try herbal liver-support supplements like milk thistle (after medical advice)

  • Manage underlying conditions like obesity, hepatitis, or fatty liver disease



Can fasting reduce SGOT and SGPT?

Intermittent fasting, when done correctly and under guidance, may improve liver enzyme levels by reducing fat accumulation and improving insulin sensitivity. However, prolonged or extreme fasting may have the opposite effect. Always consult a doctor before starting any fasting regimen if you have liver concerns.

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